The importance of Vitamin C & the efficacy of liposomal application has been studied extensively - providing us with a substantial amount of evidence through reliable resources.
We have summarised some of this evidence to share with you.
We welcome all of your questions & comments to our information email - info@ranublume.com.au -
We look forward to hearing from you!
References
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2. Hinek, A., Kim, H. J., Wang, Y., Wang, A. & Mitts, T. F. Sodium L-ascorbate enhances elastic fibers deposition by fibroblasts from normal and pathologic human skin. J Dermatol Sci 75, 173-182, do i:
10.1016/j.jdermsci.2014.05.011 (2014).
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13. Tebbe, B. et al. L-ascorbic acid inhibits UVA-induced lipid peroxidation and secretion of IL-lalpha and IL-6 in cultured humant keratinocytes in vitro. The journal of investigative dermatology 108,302-306, doi:10.1111/1523-1747.ep12286468 (1997).
14. Duarte, T. L., Cooke, M. S. & Jones, G. D. D. Gene expression profiling reveals new protective roles for vitamin C in human skin cells. Free Radical Biology and Medicine 46, 78-87, doi:https://doi.org/10.1016/i.freeradbiomed.2008.09.028 (2009).
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17. Fitzpatrick, R. E. & Rostan, E. F. Double-blind, half-face study comparing topical vitamin C and vehicle for rejuvenation of photodamage. Dermatologic surgery : official publication for American Societyfor Dermatologic Surgery [et alJ 28, 231-236, doi:10.1046/j.1524-4725.2002.01129.x (2002).
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19. Valacchi, G. et al. Vitamin C Compound Mixtures Prevent Ozone-induced Oxidative Damage in Human Keratinocytes as initial Assessment of Pollution Protection. PLOS One 10, e0131097, doi:10.1371/journal.pone.0131097 (2015).
20. Rodero, M. P. & Khosrotehrani, K. Skin wound healing modulation by macrophages. Internationaljournal of clinical and experimental pathology 3, 643-653 (2010).
21. Xu, T. H. et al. Split-face study of topical 23.8% L-ascorbic acid serum in treating photo-aged skin. Journal of drugs in dermatology: JDD 11, 51-56 (2012).
22. Tajima, S. & Pinnell, S. R. Ascorbic acid preferentially enhances type I and Ill collagen gene transcription in human skin fibroblasts. Journal of Dermatological Science 11, 250-253, doi:101016/0923-1811(95)00640-0 (1996).
23. Phillips, C. L., Combs, S. B. & Pinnell, S. R. Effects of ascorbic acid on proliferation and collagen synthesis in relation to the donor age of human dermal fibroblasts. The Journal of investigative dermatology 103, 228-232, doi:10.1111/1523-
1747.ep12393187 (1994).
24. Kishimoto, Y. et al. Ascorbic acid enhances the expression of type I and type 4 collagen and SVCT2 in cultured human skin fibroblasts. Biochemical and biophysical research communications 430, 579-584, doi:IO.1016/j.bbrc.2012.11.110 (2013).